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Notably, patients with mutations in GGT1 often present with developmental disorders, accumulation of GSH (glutathionaemia and glutathionuria) and reduced circulating levels of cystine 25

The World Health Organization (WHO) defines anemia as hemoglobin below 13 g/dL in adult males, below 12 g/dL in non-pregnant adult females, and below 11 g/dL in pregnant women

Complementing immune regulation, Clostridium rebalances gut microbiota homeostasis by enriching beneficial taxa and inhibiting pro-inflammatory bacterial overgrowth and reinforces intestinal barrier integrity by upregulating tight-junction proteins and mucin secretion, thereby blocking the translocation of pathogens and antigens that initiate systemic autoimmunity

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